Coronavirus and Vaccine Development
Coronavirus Vaccine Update: In addition to VBI Vaccines Inc. (Ottawa, Canada), the following firms are as of 27 March 2020 beginning Phase 1 testing Phase I vaccine candidates Company: Moderna Vaccine candidate: mRNA-1273 Details: Moderna is the Massachusetts-based biotech company behind mRNA-1273, a vaccine candidate developed using prior studies of related coronaviruses, such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). Study Design: A Phase 1, open-label, dose-ranging clinical trial of 45 healthy participants between 18-55 years old Institution: Kaiser Permanente Washington Health Research Institute Status: Recruiting completed 19 March 2020 ClinicalTrials.gov Identifier: NCT04283461 Funding: NIAID Company: CanSino Biologics Vaccine candidate: Ad5-nCoV Details: China’s CanSino Biologics has developed a recombinant novel coronavirus vaccine that incorporates the adenovirus type 5 vector (Ad5). Study Design: A Phase 1 cl